Abstract: Premature explosion accident is one of the main threatens to safety production in high-temperature zone of open-cast coal. To find out the preventive measure of the premature explosion accident, 2 conditional events and 16 basic events such as thermodetector failure and excessive deep hole in fire area are presented, through accident-causing analysis of premature explosion fault in fire zone of open-pit coal mine. Based on those events, premature explosion fault tree of open-pit coal mine is constructed. Combined with the qualitative analysis results of the ATA and the actual situation of some open-cast coal in Ningxia, some corresponding measures such as blasting zoning management of high-temperature area and establishing operations team of high-temperature blasting and multipartite temperature measurement are suggested to prevent premature explosion accident in high-temperature zone of open-pit coal mine, which obtains good results in the practice of the blasting operation and provides a good reference for similar engineering.